| 新化合物吡唑并嘧啶衍生物(BDO-1)和哒嗪酮衍生物(PDZ-1)的诱导抗病性研究 |
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投稿时间：2018-03-23
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| 引用本文：石延霞,张晓慧,谢学文,等.新化合物吡唑并嘧啶衍生物(BDO-1)和哒嗪酮衍生物(PDZ-1)的诱导抗病性研究[J].农药学学报,2018,20(6):721-728. |
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| 基金项目:国家重点研发计划项目（2017YFD0200904）；中国农业科学院科技创新工程（CAAS-ASTIP-IVFCAAS）；农业部园艺作物生物学与种质创制重点实验室（IVF2016） |
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| 中文摘要:吡唑并嘧啶衍生物（（E）-N-（2-氟-4-三氟甲基苯乙烯基）-1-甲基-1H-吡唑并[3，4-d]嘧啶-4-胺，简称BDO-1）和哒嗪酮衍生物（4-羟基-1-（4-甲氧基苯基）-6-氧代-1，6-二氢吡嗪-3-甲酸甲酯，简称PDZ-1）是由华东理工大学创制并合成的新化合物，本研究分别测定了其离体抑菌活性及其诱导抗病活性，并对田间应用技术进行了研究。结果表明：离体抑菌试验结果显示，BDO-1和PDZ-1对供试黄瓜的尖孢镰孢菌和多主棒孢菌并无杀菌活性；温室盆栽试验发现，2个化合物对7种蔬菜病害具有明显的诱导抗病活性，其中：BDO-1在10 mg/L下对黄瓜细菌性角斑病、黄瓜棒孢叶斑病、黄瓜枯萎病、黄瓜霜霉病、番茄早疫病、番茄灰叶斑和辣椒疫病的防治效果分别为58.81%、61.79%、69.88%、64.14%，54.42%、54.85%和63.59%；PDZ-1在10 mg/L下对黄瓜细菌性角斑病和黄瓜棒孢叶斑病的防治效果分别为62.33%和59.15%。田间防治效果验证结果表明，BDO-1和PDZ-1对黄瓜枯萎病的防治效果分别为62.95 %和48.45%。研究发现，BDO-1和PDZ-1在质量浓度为10 mg/L、诱导5次、每次间隔5d的条件下施用，对黄瓜枯萎病和棒孢叶斑病可发挥最佳防治效果。 |
| 中文关键词:吡唑并嘧啶 哒嗪酮 诱导抗病性 黄瓜枯萎病 黄瓜棒孢叶斑病 |
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| Study on induced disease resistance of two novel derivates: a pyrazolopyrimidine derivative BDO-1 and a pyridazinone derivative PDZ-1 |
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| Abstract:A pyrazolopyrimidine derivative ((E)-N-(2-fluoro-4-(trifluoromethyl)styryl)-1-methyl-1H-pyrazolo [3,4-d]pyrimidin-4-amine, BDO-1) and a pyridazinone derivative (methyl 4-hydroxy-1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylate, PDZ-1), were first synthesised by researchers from East China University of Science and Technology. In this study, the potential inducing systemic aquired resistance and the field application techniques for these two derivatives were investigated. The results showed that BDO-1 and PDZ-1 exhibited no fungicidal effect against Fusarium oxysporum and Corynespora cassiicola. Pot experiments in the greenhouse revealed that those two compounds have the potential to induce systemic aquired resistance to seven vegetable diseases. BDO-1 demonstrated good control efficacies at the concentration of 10 mg/L against cucumber bacterial angular leaf spot, cucumber corynespora leaf spot, cucumber wilt, cucumber downy mildew, tomato early blight, tomato gray leaf spot and pepper phytophthora blight, with the efficacies of 58.81%, 61.79%, 69.88%, 64.14%, 54.42%, 54.85% and 63.59%, respectively. At the same concentration, PDZ-1 also exbibited good control efficacies against cucumber bacterial angular leaf spot and corynespora leaf spot, which were 62.33% and 59.15%, respectively. Field efficacies of BDO-1 and PDZ-1 on cucumber wilt were 62.95 % and 48.45%, respectively. Finally, this research also demonstratde that the best control efficacies against cucumber fusarium wilt and cucumber corynespora leaf spot can be achieved for both BDO-1 and PDZ-1 under the same conditions (optimum inducing concentration of 10 mg/L, inducing for 5 times at interval of 5 days). |
| Key words:pyrazolopyrimidine pyridazinone induced disease resistance cucumber wilt cucumber corynespora leaf spot |
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